One exception to this is if you are playing as Lazarus or have Lazarus' Rags - you will respawn in the same room and get the kill, Plan C is 5 times rarer than other items in the same item pool, making it less likely to appear, UNLOCK: Unlock this item by defeating Greedier Mode with Lazarus, Item Pool: Shop, Devil Room, Curse Room, Red Chest, Demon Beggar, When used, the D1 duplicates 1 random pickup in the current room. Stat Down becomes Stat Up, 'Bad Trip' turns into 'Balls of Steel' and 'Amnesia' turns into 'I can see forever', * astrology, astronomy, item room, treasure room, item room pool, blue glow, m, Balances out your main stats to bring the high and low stats closer to an average value, All future stat upgrading items will now instead spread out across all other stats. Join. THIS VIDEO IS OUTDATED! More items consumed = more chance for this effect. ), UNLOCK: Unlock this item by beating Blue Womb (Hush) with Cain, Gives Isaac a familiar golden Censer which creates a huge aura of light that slows down any enemies inside it, UNLOCK: Unlock this item by beating Greed Mode with Maggy, A familiar beggar similar to Bum Friend that follows Isaac and collects keys, giving random chests in return, UNLOCK: Unlock this item by beating Greed Mode with Lazarus, Item Pool: Item Room, Secret Room, Key Beggar, *, grey, gray, black, face, stone, rock, baby, A bag that follows Isaac and drops a random Rune or Soul Stone every 7 or 8 rooms, UNLOCK: Unlock this item by beating the Isaac boss with Lilith, A familiar angel which follows Isaac and fires Sacred Heart tears which deal 10 damage at -25% shot speed and a reduced fire rate, Item Pool: Item Room, Angel Room, Greed Mode Angel Room, This item causes enemy projectiles to be able to hit other enemies. Flies spawned from a Mulligan dying, When used, the Mega Bean will freeze all enemies in the current room for a couple of seconds, deal 5 damage and poison any enemies in close proximity and send a wave of spikes across the room in the direction you are facing, The enemies in close range will take 5 damage then have a poison over time effect which deals your tear damage 4 or 6 times, The spike wave will deal 10 damage to any enemies in contact with it. The only way to remove it is via having a second trinket slot (Mom's Purse, Belly Button) or absorbing it (Marbles, Smelter, Gulp! Blood Donation machines, UNLOCK: Unlock this item by beating the Isaac boss with The Lost, * item room, treasure room, item room pool, red, isaacs heart, A familiar ghost that follows Isaac around and chases enemies close-by, damaging them for 2 contact damage and causing a fear effect, * item room, treasure room, item room pool, white, lil' haunt, A familiar beggar similar to Bum Friend that follows Isaac and collects red hearts, giving Isaac black hearts, pills, cards, runes or spiders in return, For every 1.5 red hearts he takes, he will give a reward, Reward chances: Black Heart - 40%, Card/Rune - 20%, Pill - 20%, Blue Spider - 10%, Spider 10%, Item Pool: Item Room, Devil Room, Demon Beggar, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, celebrate good times come on, the lost item pool, qt 3.14, dark bum, otp, damn it reddit, horns, grey, gray, smile, A very large orbital that moves around Isaac very slowly, blocking shots and dealing 2 contact damage per tick, Affects the speed of all other orbitals, slowing them down a lot (NOTE: This effect does not happen until you get a new orbital after Big Fan), Does not count as one of your three standard orbital slots, * item room, treasure room, item room pool, fat, brown, An adorable friendly blue spider that walks around the room laying other blue spiders which attack enemies, She can only spawn a maximum of up to 5 spiders at a time and will only do so while there are enemies in the room, REPENTANCE - Sissy Longlegs now charms enemies upon contact, * item room, treasure room, sissy longlegs item room pool, qt 3.14, dark bum, otp, damn it reddit, blue, derpface, Spawns a friendly Mulligan that walks around the room. He behaves the same as how Esau works with Jacob, following your exact movements, Disappears after the current room or if he takes enough damage and dies, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Forgotten, Creates 6 wisps, similar to the Book of Virtues effect, Mosts wisps will be the standard blue ones, but have a chance to have random special properties, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Bethany, Spawns Esau as a temporary familiar, who copies your exact movements the same as how the Jacob & Esau character works, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Jacob, Once picked up, you gain unlimited key use for the rest of the floor, Using a 'Bombs are Key' pill with this effect will swap your Gold Key for a Gold Bomb, Once picked up, you gain unlimited bomb use for the rest of the floor, Using a 'Bombs are Key' pill with this effect will swap your Gold Bomb for a Gold Key, UNLOCK: Unlock this item by beating challenge #23 (Blue Bomber), Fully charges your active item when picked up, Also, you take a full heart of damage when picked up. 'One Makes you Larger' pills, Magic Mushroom etc, *, mtg, card, magic, gathering, green, brown, giant growth, Spawns 3 random cards on the floor when used, When used, this card will slow down enemies, Isaac's tears by -1 Shot Speed, but speed up Isaac's movement speed by +0.50 for the rest of the current room, UNLOCK: Unlock this item by getting both the Broken Watch and the Stop Watch in your collection, When used, removes the price tag from all items in the current shop or devil deal, making everything free, The effect of the Credit Card only lasts for the current room, UNLOCK: Unlock this card by beating Challenge #10 (Cursed!). As Azazel they fire brimstone and as The Forgotten they use a bone club, At the beginning of all future floors, two portals will appear, that can take you to either the Boss room (Red portal), Item room (Yellow portal) or Secret room (Blue portal), After Chapter 3 (The Depths floors) only one portal will spawn, Portals disappear if you leave the starting room, Every time an enemy dies, a random familiar spawns where it was killed for the rest of the room, The familiar cannot move, but continues to do its usual abilities, Possible familiars include: Abel, Boiled Baby, Brother Bobby, Sister Maggy, Little Steven, Demon Baby, Multidimensional Baby, Freezer Baby, Rotten Baby, Harlequin Baby, Ghost Baby, Guardian Angel, Lil Brimstone, Robo-Baby and Seraphim, Every 5 seconds you become spiky for a second, becoming immune and dealing 40 contact damage to any enemies that touch you, The effect is indicated by 4 white flashes, where the item activates on the 4th flash, If timed well, can be used to enter curse rooms and open spiky chests without taking damage. Larry Jr.) it will split them into 2 smaller enemies with half the number of sections they used to have, If the enemy normally has a mechanic that splits it (e.g. you can wish list it on steam here > mewgenics.com more info dropping on Halloween! achievement (complete a victory lap, defeating the lamb boss), Horf! After killing a 25 more enemies, it transforms again dealing 15 damage and destroying obstacles it charges into. It works great. cash money, When used, Isaac gains homing shots and +3.0 Range Up for the current room, Counts as 1 of 3 book items needed towards the Bookworm transormation, * library pool, library room, book room pool, item room, treasure room, item room pool, Room Item Pools: Item Room Boss Room Devil Room Angel Room Shop Secret Room Challenge Room Library. Counts as 1 of 3 book items needed towards the Bookworm transformation. If you didn't find one before this point, there will be a tinted Skull somewhere on Depths II, which contains a Fool card when blown up. Following the path takes you to an abandoned mineshaft, which leads you to a pedestal with the Knife Piece. card will teleport you to the I AM ERROR room, UNLOCK: Unlock this item by beating the Isaac boss with Eden, * secret room pool, shop room pool, shop item pool, item room, treasure room, item room pool, This effect is stackable, *, the lost item pool, pink, red, guts, intestine, tube, Gives Isaac a higher chance to find hearts from drops after clearing a room and from chests, * , the lost item pool, red, purple, childs heart, child heart, UNLOCK: Unlock this item by beating the Dark Room with Judas, Gives Isaac a higher chance to find keys and chests, Grants a secondary chance of any non-specific heart drop turning into a soul heart, * , the lost item pool, white, grey, gray, circle, round, moms pearl, The fire rate increase is applied in such a way that the higher your tear stat is, the more effective Cancer is, Breaks the normal fire rate cap, allowing you to fire faster than the normal maximum, You have a chance when taking damage to gain +1.8 Damage Up for the rest of the room, Gives Isaac a higher chance to find bombs, Picking up the Match Stick is the only way to remove the Tick trinket, UNLOCK: Unlock this item by blowing up 20 shop keepers (this includes the ones in the secret room), When you take damage while on 1/2 a heart, you are teleported back to the previous room. UNLOCK: Unlock this item by beating the Boss Rush with Azazel, * devil pool, devil room pool, devil deal, grey, gray, bloody, Spawns a trapdoor at Isaac's feet which allows him to travel to the next floor, Digging in certain spots with objects or markings on the floor will guarantee a crawlspace once per floor, In Sheol, Cathedral, Chest and Dark Room this item either opens a Crawl Space, or does nothing, Cannot spawn a trapdoor directly infront of a secret room entrance, Can destroy rocks if used when Isaac is flying over a rock, * secret room pool, devil pool, devil room pool, devil deal, silver, grey, gray, dig, spade, shovel, Counts as 1 of 3 astrology items needed in the same run to unlock Planetariums, * shop room pool, shop item pool, item room, treasure room, item room pool, brown, pink, When used, spawns a Monstro which will jump on a random enemy in the room, dealing 120 damage and destroying nearby obstacles, UNLOCK: Unlock this item by beating the Basement II for the first time, * item room, treasure room, item room pool, white, grey, gray, bloody, monstros tooth, monstro tooth, Everytime you fire a tear, there is a chance that you will also fire three more tears in all cardinal directions, The chance to fire 4-way tears is affected by your luck stat and at +15 Luck it will activate every time, At +0 luck the effect has a 30% chance to activate, UNLOCK: Unlock this item by beating Lokii for the first time, * item room, treasure room, item room pool, grey, gray, devil, lokis horns loki horns, A familiar that follows Isaac and charges forwards, dealing 3.5 damage per tick to any enemies it comes into contact with, REPENTANCE - The damage tick rate on Little Chubby has been increased, UNLOCK: Unlock this item by beating the Caves II for the first time, * item room, treasure room, item room pool, yellow, smile, face, bug, Tears now have a chance of slowing enemies and their projectiles for 2.5 seconds, The chance to slow enemies is affected by your luck stat and at +15 Luck it will activate every time, * item room, treasure room, item room pool, black, grey, gray, red, bug, Has a chance to drop when exploding a tinted rock, UNLOCK: Unlock this item by destroying 100 tinted rocks, * tinted rock, marked rock, grey, gray, lump, white, Reveals adjacent rooms up to 2 rooms away, this includes revealing if you're next to a Secret Room or Super Secret Rooms, Gives Isaac a slight glow when Curse of Darkness is active, Blocks damage from projectiles falling from above, * item room, treasure room, item room pool, spelunky, miner, mining, helpmet, light, purple, olmec yama Tears continue to fire from your left eye, The laser deals damage equal to 1/7th of your tear damage, but very rapidly, The laser can apply status effects (e.g. Rock Bottom is an unlockable passive item added in The Binding of Isaac: Repentance . Cannot be obtained and has no use for any other character, Birthright is a Shop item that has unique effects depending on what character you're playing as, This is the item Tainted Blue Baby (???) Items for 15c, hearts for 3c, sacks for 7c, UNLOCK: Unlock this card by defeating challenge #44 (Red Redemption), Activates a random effect from a Dice room, See the dice icon above for each possible effect, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Cain, All enemies in the current room are slowed and take double damage, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Samson, You turn into the Keeper, gaining triple shot, -0.1 Speed Down for 30 seconds, Enemies drop random coins while this effect is active, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Keeper, Activates the Book of the Dead effect, spawning a bone orbital or charmed Bony for each enemy killed in the current room, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Forgotten, When used, this card activates 5 random pill effects one after the other, UNLOCK: Unlock this card by defeating challenge #45 (DELETE THIS), Activates The Bible effect (granting flight) and gives a Seraphim familiar for 30 seconds, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Azazel, Spawns 6 clusters of rocks and objects that normally appear on this floor, Rocks have a pretty good chance to become tinted rocks, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Apollyon, Removes your oldest item and spawns 2 pedestal items from the current room's pool, Can remove either passive or active items, Doesn't remove your character's starting items, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Isaac, Teleports you to the ultra secret room on the floor, The ultra secret room is a red room containing an item from the angel room item pool. Basement 2: 2 Bombs + 2 Keys, Caves 1: 1 Boss Item. the lost item pool, purple, cross, Item Pool: Curse Room, Devil Room, Demon Beggar, * curse room pool, devil pool, devil room pool, devil deal, red, 666, Item Pool: Devil Room, Curse Room, Demon Beggar, * curse room pool, devil pool, devil room pool, devil deal, piece of paper, bloody paper, contract, Krampus Head) can still spawn, Bible drops caused by the Rosary item are not prevented by this trinket, *, stop, red, circle, line, cross, entry, warning, Causes your familiars to stay closer to each other, Poop in the environment will now explode when destroyed, While held you have an increased chance for Black Poops to spawn, which deal damage to all enemies in the room when destroyed, Gives The Poop active item a chance to spawn a Black Poop too. soul or black hearts, Your devil deal chance isn't ruined by this item taking away red hearts. Donation machines become fixed if they were jammed before using the R Key, Isaac now has a chance to fire a fist instead of normal tears, which have a much higher knockback effect and confuse enemies for a few seconds, Enemies that are knocked back will take 10 damage and knock back any enemy they are knocked into, dealing damage to them as well, An active item that allows you to throw an eraser at any enemy, which will kill it and prevent it from appearing for the rest of the run, Enemies that are erased create a puff of smoke instead of spawning, Works on bosses, except it doesn't kill them it just deals 15 damage, Can only be used once per floor - batteries also cannot be used to recharge it to bypass this restriction, The first use will raise it above your head, then by pressing the fire button it will be thrown in that direction, Recharge time: 1 room (Can only be used once per floor), When used, this item will give you +1 Rotten Heart, Rotten Hearts act as red hearts and each one you currently have spawns 2 blue flies upon successfully clearing a room, UNLOCK: Unlock this item by defeating Mother in the Corpse II as Maggy, Enemies now create a soul upon death, which is automatically sucked into the Urn giving it +1 charge. Increases the maximum heart limit to 18. Use the arrow keys or WASD keys to move around. ?, Satan and The Lamb as Tainted Bethany, Taking damage gives you a chance to spawn a flame orbital, similar to the ones created by Book of Virtues, Entering an Angel Room gives you +5 flame orbitals. No longer reduces your devil/angel room chances when used, * item room, treasure room, item room pool, the lost item pool, bomb, tnt, clock, red, When used, causes all enemies in the current room to run away from Isaac in fear for 5 seconds. Items - The Official Binding of Isaac: IPECAC Wiki Stealing an item has a chance to fail (a buzzer sound will play if it fails), Enemies: Attacks the enemy until either the ghost or the enemy dies, Doors: Opens the door, even if it is locked, Secret room entrances: Explodes and opens the entrance, Boss rush door: Will open the Boss Rush door from either side, allowing you get into and escape the Boss Rush, Slot machines, dead shopkeepers: Charges towards them and explodes them, Added as part of the Afterbirth+ Booster Pack #3. Bad Trip becomes Balls of Steel. Possible doors include any needing a key to open (Item Room, Shop, Alt Path doors), secret rooms and crawl spaces, Cracked Orb can also reveal the location of the red room that contains a pedestal item. the eternal hearts that drop in angel themed super secret rooms, All heart drops from Ace of Hearts will be Black Hearts, UNLOCK: Unlock this item by beating Satan with Azazel, *, black, devil, pointy, daemons tail, demons tail, demon tail, Dying in a sacrifice room while holding this trinket will unlock The Lost character, After The Lost is unlocked, dying anywhere with this trinket will bring you back to life as The Lost and the trinket will be deleted, When playing as Tainted Lost, you don't swap to being regular Lost, it simply acts as an extra life, UNLOCK: Unlock this item by beating Dark Room with Isaac, Everytime you pick up a coin, you fart, inflicting poison damage to nearby enemies, Greatly increases the chance of coins dropping from poops, Tears now move forwards at right angles, shifting left and right across the room, Increases your range stat by +10.0 while held but due to the fire pattern, your tears travel a similar distance to normal, Your tears now whip across the room at a very high shot speed, Shot speed gives your tears more effective range, but doesn't increase your range stat directly, Has a 22.22% chance to respawn with 3 Soul hearts as Blue Baby when you die, UNLOCK: Unlock this item by beating Satan with Lazarus, Everytime Isaac takes damage, one blue fly will spawn, * , the lost item pool, green, red, bloody, dead, Isaac's tears have a chance to poison enemies, The poison effect leaves a damage over time, which deals 4 or 6 damage per tick, The chance to poison enemies is affected by your luck stat and at +18 Luck it will activate every time, Isaac now has a chance to make a spectral and piercing tear, The chance to fire a piercing tear is affected by your luck stat and at +18 Luck it will activate every time, While held, this trinket gives a random mushroom effect each room, Possible mushrooms include: Mini Mush, Odd Mushroom (Thin), Odd Mushroom (Thick), The Compass, *, ping, pong, paddle, grey, gray, mushroom, While at 1/2 a red heart of health, you gain a Little Steve familiar that follows you and shoots homing tears, REPENTANCE - Umbilical Cord now has a high chance to spawn a Gemini familiar for the room when Isaac takes damage. arrow, Causes your friendly blue spiders and flies to become bigger and do x2 more damage, Allows Mom's Wig to spawn a maximum of 10 spiders at once instead of 5, Fly and spider familiars become stronger similar to BFFS, * shop room pool, shop item pool, blue, fat, Two items now spawn after beating a boss fight and the boss rush, however only one can be taken, The additional item will pick from the Boss Item Pool, Unlocked by donating to the donation machine in the shop, UNLOCK: Unlock this item by donating 50 pennies to the Shop, * shop room pool, shop item pool, white, question mark, square, theres options, * shop room pool, shop item pool, purple, paper, ticket, Isaac can now hold 2 cards or runes at once. (2% chance for the end of room drop to become a trinket), If a trinket has been smelted, it won't appear a second time unless the entire trinket pool is exhausted or you restart the run (e.g. Blood Bag) it will be rerolled into a random Item Room item, Cannot remove Azazel's Brimstone laser, or The Lost's Holy Mantle, REPENTANCE - Full run reroll effects are now able to remove heart containers and transformations if losing the respective items during the reroll, UNLOCK: Unlock this item by blowing up 30 slot machines, * item room, treasure room, item room pool, dice pip, starting, pyramid, green, triange, When used, 'devolves' all enemies in the room which are currently alive into another weaker type of enemy, * item room, treasure room, item room pool, DIO, dice pip, orange, brown, turban, When used, copies the effect of the card you are currently holding without consuming it, The charge time of this item depends on the quality of the card you're holding, Using this with the ?
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